Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL879635

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to leukotriene B4 receptor on intact human PMNs by displacing radioligand [3H]LTB4
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Leukotriene B4 receptor 1 (CHEMBL3911)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

(E)-3-[[[[6-(2-carboxyethenyl)-5-[[8-(4- methoxyphenyl)octyl]oxy]-2-pyridinyl]-methyl]thio]methyl]benzoic acid and related compounds: high affinity leukotriene B4 receptor antagonists.
Daines RA, Chambers PA, Eggleston DS, Foley JJ, Griswold DE, Haltiwanger RC, Jakas DR, Kingsbury WD, Martin LD, Pendrak I.
J Med Chem (1994) 37 : 3327 -3336
PubMed 7932560 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.92 7.92

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL49302 1 7.92

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL49302 IC50 = 12.0 nM 7.92