Assay Detail
Functional
CHEMBL879739
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Tested for cytotoxic concentration required to reduce the viability of MT-4 cells by 50%
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MT4 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
New 2-(1-adamantylcarbonyl)pyridine and 1-acetyladamantane thiosemicarbazones-thiocarbonohydrazones: cell growth inhibitory, antiviral and antimicrobial activity evaluation.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 6 | 5.17 | 5.62 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL352671 | — | — | 1 | 5.62 |
| CHEMBL160097 | — | — | 1 | 5.58 |
| CHEMBL350317 | — | — | 1 | 5.15 |
| CHEMBL162738 | — | — | 1 | 5.12 |
| CHEMBL350197 | — | — | 1 | 5.00 |
| CHEMBL162893 | — | — | 1 | 4.56 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL352671 | — | EC50 | = | 2400.0 | nM | 5.62 |
| CHEMBL160097 | — | EC50 | = | 2600.0 | nM | 5.58 |
| CHEMBL350317 | — | EC50 | = | 7100.0 | nM | 5.15 |
| CHEMBL162738 | — | EC50 | = | 7500.0 | nM | 5.12 |
| CHEMBL350197 | — | EC50 | = | 10100.0 | nM | 5.00 |
| CHEMBL162893 | — | EC50 | = | 27300.0 | nM | 4.56 |