Assay Detail
Binding
CHEMBL879774
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Binding affinity of compound towards H+/K+ ATPase for activation was determined
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Potassium-transporting ATPase alpha chain 1 (CHEMBL3919) ↗| Type | SINGLE PROTEIN |
| Organism | Sus scrofa |
Publication
Reversible inhibitors of the gastric (H+/K+)-ATPase. 1. 1-Aryl-4-methylpyrrolo[3,2-c]quinolines as conformationally restrained analogues of 4-(arylamino)quinolines.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 6.54 | 6.54 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL95108 | — | — | 1 | 6.54 |
| CHEMBL151251 | — | — | 1 | 6.54 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL95108 | — | Ki | = | 290.0 | nM | 6.54 |
| CHEMBL151251 | — | Ki | = | 290.0 | nM | 6.54 |