Assay Detail
Binding
CHEMBL880609
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Inhibitory activity against 5-hydroxytryptamine 1A receptor in rat
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
2-Alkyl-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indoles as novel 5-HT6 receptor agonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.28 | 6.37 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL194305 | — | — | 1 | 6.37 |
| CHEMBL364005 | — | — | 1 | 6.18 |
| CHEMBL267615 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL194305 | — | IC50 | = | 430.0 | nM | 6.37 |
| CHEMBL364005 | — | IC50 | = | 660.0 | nM | 6.18 |
| CHEMBL267615 | — | IC50 | > | 1000.0 | nM | - |