Assay Detail
Functional
CHEMBL881122
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Inhibitory concentration required against vaccinia virus in Vero cell culture
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Vaccinia virus |
| Cell Type | Vero |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
A new approach to the synthesis of optically active alkylated adenine derivatives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 4.59 | 4.90 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL113930 | — | — | 1 | 4.90 |
| CHEMBL494759 | (S)-DHPA | — | 1 | 4.47 |
| CHEMBL112159 | — | — | 1 | 4.39 |
| CHEMBL114867 | — | — | 1 | - |
| CHEMBL321500 | — | — | 1 | - |
| CHEMBL326139 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL113930 | — | IC50 | = | 12500.0 | nM | 4.90 |
| CHEMBL494759 | (S)-DHPA | IC50 | = | 34000.0 | nM | 4.47 |
| CHEMBL112159 | — | IC50 | = | 41000.0 | nM | 4.39 |
| CHEMBL114867 | — | IC50 | > | 350000.0 | nM | - |
| CHEMBL321500 | — | IC50 | > | 500000.0 | nM | - |
| CHEMBL326139 | — | IC50 | > | 300000.0 | nM | - |