Assay Detail
Binding
CHEMBL881500
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibitory activity against 5-hydroxytryptamine 4 receptor in guinea pig
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Cavia porcellus |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
2-Alkyl-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indoles as novel 5-HT6 receptor agonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.19 | 7.36 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL267615 | — | — | 1 | 7.36 |
| CHEMBL364005 | — | — | 1 | 6.21 |
| CHEMBL194305 | — | — | 1 | 5.01 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL267615 | — | IC50 | = | 44.0 | nM | 7.36 |
| CHEMBL364005 | — | IC50 | = | 620.0 | nM | 6.21 |
| CHEMBL194305 | — | IC50 | = | 9800.0 | nM | 5.01 |