Assay Detail
Binding
CHEMBL881886
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Inhibitory concentration against Glucocorticoid receptor
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Expert |
Publication
Is antagonism of E/Z-guggulsterone at the farnesoid X receptor mediated by a noncanonical binding site? A molecular modeling study.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.49 | 5.76 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL402063 | E-GUGGULSTERONE | — | 1 | 5.76 |
| CHEMBL410683 | GUGGULSTERONE | — | 1 | 5.22 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL402063 | E-GUGGULSTERONE | IC50 | = | 1740.0 | nM | 5.76 |
| CHEMBL410683 | GUGGULSTERONE | IC50 | = | 6060.0 | nM | 5.22 |