Assay Detail
Binding
CHEMBL882123
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Inhibitory concentration against thromboxane A2 synthase
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Designed multiple ligands. An emerging drug discovery paradigm.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 7.39 | 8.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL277689 | SAMIXOGREL | 2.0 | 1 | 8.40 |
| CHEMBL46571 | — | — | 1 | 7.50 |
| CHEMBL198965 | — | — | 1 | 7.11 |
| CHEMBL105139 | — | — | 1 | 7.05 |
| CHEMBL102692 | — | — | 1 | 6.87 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL277689 | SAMIXOGREL | IC50 | = | 4.0 | nM | 8.40 |
| CHEMBL46571 | — | IC50 | = | 32.0 | nM | 7.50 |
| CHEMBL198965 | — | IC50 | = | 78.0 | nM | 7.11 |
| CHEMBL105139 | — | IC50 | = | 90.0 | nM | 7.05 |
| CHEMBL102692 | — | IC50 | = | 135.0 | nM | 6.87 |