Assay Detail
Binding
CHEMBL882289
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Binding affinity to phenylethanolamine N-methyltransferase(PNMT) in bovine
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Phenylethanolamine N-methyltransferase (CHEMBL2331) ↗| Type | SINGLE PROTEIN |
| Organism | Bos taurus |
Publication
Conformational requirements of substrates for activity with phenylethanolamine N-methyltransferase.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 4.95 | 5.03 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL46439 | — | — | 1 | 5.03 |
| CHEMBL14346 | 1,2,3,4-TETRAHYDROISOQUINOLINE | — | 1 | 5.00 |
| CHEMBL30294 | — | — | 1 | 4.82 |
| CHEMBL296679 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL46439 | — | Ki | = | 9400.0 | nM | 5.03 |
| CHEMBL14346 | 1,2,3,4-TETRAHYDROISOQUINOLINE | Ki | = | 10000.0 | nM | 5.00 |
| CHEMBL30294 | — | Ki | = | 15000.0 | nM | 4.82 |
| CHEMBL296679 | — | Ki | = | 176000.0 | nM | - |