Assay Detail
Functional
CHEMBL882290
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Inhibitory activity against IgG antibody production in PBMC
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Novel naphthalene derivatives as inhibitors of human immunoglobulin E antibody production.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 5.70 | 7.38 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL423693 | — | — | 1 | 7.38 |
| CHEMBL337497 | — | — | 1 | 5.63 |
| CHEMBL130572 | — | — | 1 | 5.37 |
| CHEMBL130102 | — | — | 1 | 4.42 |
| CHEMBL128052 | — | — | 1 | - |
| CHEMBL133470 | — | — | 1 | - |
| CHEMBL336392 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL423693 | — | IC50 | = | 42.0 | nM | 7.38 |
| CHEMBL337497 | — | IC50 | = | 2320.0 | nM | 5.63 |
| CHEMBL130572 | — | IC50 | = | 4300.0 | nM | 5.37 |
| CHEMBL130102 | — | IC50 | = | 38000.0 | nM | 4.42 |
| CHEMBL128052 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL133470 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL336392 | — | IC50 | > | 10000.0 | nM | - |