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Assay Detail

CHEMBL882464

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibitory constant against human recombinant Beta-1,4-galactosyltransferase I
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Expert

Target

Beta-1,4-galactosyltransferase 1 (CHEMBL4384)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Rational design, synthesis, and characterization of novel inhibitors for human beta1,4-galactosyltransferase.
Takaya K, Nagahori N, Kurogochi M, Furuike T, Miura N, Monde K, Lee YC, Nishimura S.
J Med Chem (2005) 48 : 6054 -6065
PubMed 16162007 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 2 5.31 5.31

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1743884 UDP-GALACTOSE 1 5.31
CHEMBL2368692 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1743884 UDP-GALACTOSE Ki = 4910.0 nM 5.31
CHEMBL2368692 Ki = 149000.0 nM -