Compound Detail
CHEMBL1743884
UDP-GALACTOSE Enter ChEMBL ID:
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O=c1cc([C@@H]2O[C@H](COP(=O)(O)OP(=O)(O)O[C@H]3O[C@H](CO)[C@H](O)[C@H](O)[C@H]3O)[C@@H](O)[C@H]2O)[nH]c(=O)[nH]1
Basic Information
| ChEMBL ID | CHEMBL1743884 |
| Name | UDP-GALACTOSE |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | USAZACJQJDHAJH-KDEXOMDGSA-N |
2
Targets
2
Activities
2
Assay Types
0
PK Parameters
5
Publications
0
Known Names
Molecular Properties
566.3
MW (Da)
-4.72
ALogP
15
HBA
10
HBD
307.9
PSA (Ų)
0.13
QED
3
Ro5 Violations
9
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 6.17
Ki 1 meas. best 5.31
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| P2Y purinoceptor 14 CHEMBL4518 | EC50 | 6.17 | 6.17 | 671.0 | 1 |
| Beta-1,4-galactosyltransferase 1 CHEMBL4384 | Ki | 5.31 | 5.31 | 4910.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| P2Y purinoceptor 14 | EC50 | = | 671.0 | nM | 6.17 | Agonist activity at human P2Y14 receptor expressed in COS7 cells assessed as sti... | 17088057 |
| Beta-1,4-galactosyltransferase 1 | Ki | = | 4910.0 | nM | 5.31 | Inhibitory constant against human recombinant Beta-1,4-galactosyltransferase I | 16162007 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 19560364 | 10.1016/j.bmc.2009.06.005 | Putative glycosyltransferase | 4 |
| 3475471 | 10.1021/jm00391a020 | N-acetyllactosaminide alpha-1,3-galactosyltransferase | 2 |
| 3475472 | 10.1021/jm00391a021 | Unchecked | 1 |
| 16162007 | 10.1021/jm0504297 | Beta-1,4-galactosyltransferase 1 | 1 |
| 17088057 | 10.1016/j.bmcl.2006.10.081 | P2Y purinoceptor 14 | 1 |
Data from ChEMBL 36 via Core Engine