Assay Detail
Binding
CHEMBL882939
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Inhibitory concentration against prostaglandin G/H synthase
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 5 — Multiple protein complex / RNA |
| Curated By | Autocuration |
Publication
Designed multiple ligands. An emerging drug discovery paradigm.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.74 | 7.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL435907 | — | — | 1 | 7.52 |
| CHEMBL196996 | — | — | 1 | 6.41 |
| CHEMBL8846 | PRIFELONE | 2.0 | 1 | 6.30 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL435907 | — | IC50 | = | 30.0 | nM | 7.52 |
| CHEMBL196996 | — | IC50 | = | 390.0 | nM | 6.41 |
| CHEMBL8846 | PRIFELONE | IC50 | = | 500.0 | nM | 6.30 |