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Assay Detail

CHEMBL883272

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Tested for antiviral activity against HIV-1 infected human CEM-SS cell line
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type CEM-SS
Confidence 1 — Organism
Curated By Intermediate

Target

CEM-SS (CHEMBL614548)
Type CELL-LINE
Organism Homo sapiens

Publication

Rational design for cytosolic delivery of nucleoside monphosphates : SATE and DTE as enzyme-labile transient phosphate protecting groups
Perigaud C, Gosselin G, Lefebvre I, Girardet J, Benzaria S, Barber I, Imbach J
Bioorg Med Chem Lett (1993) 3 : 2521 -2526
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 3 4.76 5.30

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL85969 1 5.30
CHEMBL313908 1 4.22
CHEMBL85309 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL85969 EC50 = 5000.0 nM 5.30
CHEMBL313908 EC50 = 60000.0 nM 4.22
CHEMBL85309 EC50 > 100000.0 nM -