Assay Detail
Functional
CHEMBL883274
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Effective concentration required for evoking response in HEK293 cell
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HEK293 |
| Confidence | 3 — Cell-line / Tissue |
| Curated By | Autocuration |
Publication
4-Alkyl- and 4-cinnamylglutamic acid analogues are potent GluR5 kainate receptor agonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 5.51 | 6.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL301536 | — | — | 1 | 6.10 |
| CHEMBL275040 | KAINIC ACID | 2.0 | 1 | 4.92 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL301536 | — | EC50 | = | 800.0 | nM | 6.10 |
| CHEMBL275040 | KAINIC ACID | EC50 | = | 12000.0 | nM | 4.92 |