Assay Detail
Functional
CHEMBL884043
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Inhibitory activity against Human Enterovirus 71 (1743) B using plaque reduction assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Enterovirus |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis and antipicornavirus activity of (R)- and (S)-1-[5-(4'-chlorobiphenyl-4-yloxy)-3-methylpentyl]-3-pyridin-4-yl-imidazolidin-2-one.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.68 | 8.59 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL194616 | — | — | 1 | 8.59 |
| CHEMBL372209 | — | — | 1 | 6.77 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL194616 | — | IC50 | = | 2.6 | nM | 8.59 |
| CHEMBL372209 | — | IC50 | = | 170.0 | nM | 6.77 |