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Assay Detail

CHEMBL884049

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Inhibitory activity against human Enterovirus 71 (2086) C using plaque reduction assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Enterovirus
Confidence 1 — Organism
Curated By Intermediate

Target

Enterovirus A71 (CHEMBL612436)
Type ORGANISM
Organism Enterovirus A71

Publication

Synthesis and antipicornavirus activity of (R)- and (S)-1-[5-(4'-chlorobiphenyl-4-yloxy)-3-methylpentyl]-3-pyridin-4-yl-imidazolidin-2-one.
Chern JH, Chang CS, Tai CL, Lee YC, Lee CC, Kang IJ, Lee CY, Shih SR.
Bioorg Med Chem Lett (2005) 15 : 4206 -4211
PubMed 16054357 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.37 7.37

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL45426 1 7.37

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL45426 IC50 = 43.0 nM 7.37