Assay Detail
Functional
CHEMBL884125
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Tested for inhibitory concentration against MSV-Induced transformation of C3H/3T3 embryo murine fibroblast in vitro
10
Total Activities
10
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | C3H/3T3 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
N-aminoimidazole derivatives inhibiting retroviral replication via a yet unidentified mode of action.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 10 | 4.98 | 5.27 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL273996 | — | — | 1 | 5.27 |
| CHEMBL38470 | — | — | 1 | 5.16 |
| CHEMBL289423 | — | — | 1 | 5.16 |
| CHEMBL290159 | — | — | 1 | 4.87 |
| CHEMBL39414 | — | — | 1 | 4.42 |
| CHEMBL289210 | — | — | 1 | - |
| CHEMBL285907 | — | — | 1 | - |
| CHEMBL39115 | — | — | 1 | - |
| CHEMBL39825 | — | — | 1 | - |
| CHEMBL289785 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL273996 | — | IC50 | = | 5370.0 | nM | 5.27 |
| CHEMBL38470 | — | IC50 | = | 6900.0 | nM | 5.16 |
| CHEMBL289423 | — | IC50 | = | 6890.0 | nM | 5.16 |
| CHEMBL290159 | — | IC50 | = | 13370.0 | nM | 4.87 |
| CHEMBL39414 | — | IC50 | = | 38000.0 | nM | 4.42 |
| CHEMBL289210 | — | IC50 | > | 64600.0 | nM | - |
| CHEMBL285907 | — | IC50 | > | 11400.0 | nM | - |
| CHEMBL39115 | — | IC50 | > | 12700.0 | nM | - |
| CHEMBL39825 | — | IC50 | > | 12130.0 | nM | - |
| CHEMBL289785 | — | IC50 | > | 67700.0 | nM | - |