Assay Detail
Functional
CHEMBL884230
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Effective concentration evaluated in HEK293 cells
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HEK293 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Design and synthesis of hydroxyethylene-based peptidomimetic inhibitors of human beta-secretase.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 5.76 | 6.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL44027 | — | — | 1 | 6.00 |
| CHEMBL42908 | — | — | 1 | 5.52 |
| CHEMBL41851 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL44027 | — | EC50 | = | 1000.0 | nM | 6.00 |
| CHEMBL42908 | — | EC50 | = | 3000.0 | nM | 5.52 |
| CHEMBL41851 | — | EC50 | > | 10000.0 | nM | - |