Assay Detail
Functional
CHEMBL884247
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Compound was evaluated for the cytoprotection of CEM-SS cells by XTT cytoprotection assay through the NCI AIDS Screen
10
Total Activities
10
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | CEM-SS |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Chicoric acid analogues as HIV-1 integrase inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 10 | 4.95 | 5.44 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL31883 | — | — | 1 | 5.44 |
| CHEMBL31607 | — | — | 1 | 5.25 |
| CHEMBL31600 | — | — | 1 | 5.24 |
| CHEMBL31435 | — | — | 1 | 5.24 |
| CHEMBL30522 | — | — | 1 | 5.17 |
| CHEMBL31044 | — | — | 1 | 5.04 |
| CHEMBL282731 | CICHORIC ACID | — | 1 | 4.70 |
| CHEMBL30455 | — | — | 1 | 4.64 |
| CHEMBL29660 | CHICORIC ACID | — | 1 | 4.45 |
| CHEMBL29369 | — | — | 1 | 4.30 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL31883 | — | IC50 | = | 3640.0 | nM | 5.44 |
| CHEMBL31607 | — | IC50 | = | 5670.0 | nM | 5.25 |
| CHEMBL31600 | — | IC50 | = | 5760.0 | nM | 5.24 |
| CHEMBL31435 | — | IC50 | = | 5710.0 | nM | 5.24 |
| CHEMBL30522 | — | IC50 | = | 6700.0 | nM | 5.17 |
| CHEMBL31044 | — | IC50 | = | 9220.0 | nM | 5.04 |
| CHEMBL282731 | CICHORIC ACID | IC50 | = | 20100.0 | nM | 4.70 |
| CHEMBL30455 | — | IC50 | = | 23000.0 | nM | 4.64 |
| CHEMBL29660 | CHICORIC ACID | IC50 | = | 35500.0 | nM | 4.45 |
| CHEMBL29369 | — | IC50 | = | 50000.0 | nM | 4.30 |