Assay Detail
Binding
CHEMBL884445
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The compound was tested for the binding affinity against Dopamine receptor D1 activity is expressed as IC50 values.
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Enhanced D1 affinity in a series of piperazine ring substituted 1-piperazino-3-arylindans with potential atypical antipsychotic activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 6.46 | 8.08 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL422067 | — | — | 1 | 8.08 |
| CHEMBL343820 | — | — | 1 | 6.32 |
| CHEMBL92560 | — | — | 1 | 5.75 |
| CHEMBL92896 | — | — | 1 | 5.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL422067 | — | IC50 | = | 8.3 | nM | 8.08 |
| CHEMBL343820 | — | IC50 | = | 480.0 | nM | 6.32 |
| CHEMBL92560 | — | IC50 | = | 1800.0 | nM | 5.75 |
| CHEMBL92896 | — | IC50 | = | 2000.0 | nM | 5.70 |