Assay Detail
Functional
CHEMBL884500
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Anti-HIV activity to protect MT-4 cells from HIV-1 induced cytopathogenicity by MTT method Y181C
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MT4 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Novel indolyl aryl sulfones active against HIV-1 carrying NNRTI resistance mutations: synthesis and SAR studies.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 7.96 | 8.22 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL82106 | — | — | 1 | 8.22 |
| CHEMBL84217 | — | — | 1 | 7.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL82106 | — | EC50 | = | 6.0 | nM | 8.22 |
| CHEMBL84217 | — | EC50 | = | 20.0 | nM | 7.70 |