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Assay Detail

CHEMBL884574

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition constant against endothelin converting enzyme 1
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Expert

Target

Endothelin-converting enzyme 1 (CHEMBL4791)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Designed multiple ligands. An emerging drug discovery paradigm.
Morphy R, Rankovic Z.
J Med Chem (2005) 48 : 6523 -6543
PubMed 16220969 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 8.00 8.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL305388 1 8.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL305388 Ki = 10.0 nM 8.00