Assay Detail
Binding
CHEMBL884748
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Binding affinity towards somatostatin receptor type 5
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Discovery of iodinated somatostatin analogues selective for hsst2 and hsst5 with excellent inhibition of growth hormone and prolactin release from rat pituitary cells.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 8.30 | 8.85 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1823872 | SOMATOSTATIN | 3.0 | 1 | 8.85 |
| CHEMBL3350037 | — | — | 1 | 8.17 |
| CHEMBL262017 | — | — | 1 | 7.88 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1823872 | SOMATOSTATIN | Ki | = | 1.4 | nM | 8.85 |
| CHEMBL3350037 | — | Ki | = | 6.8 | nM | 8.17 |
| CHEMBL262017 | — | Ki | = | 13.1 | nM | 7.88 |