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Assay Detail

CHEMBL884756

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Binding
Inhibitory activity against Mandelate racemase at pH 7.5 at 25 degree C
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Pseudomonas putida
Confidence 9 — Direct single protein target
Curated By Expert

Target

Mandelate racemase (CHEMBL4739)
Type SINGLE PROTEIN
Organism Pseudomonas putida

Publication

Inhibition of mandelate racemase by the substrate-intermediate-product analogue 1,1-diphenyl-1-hydroxymethylphosphonate.
Burley RK, Bearne SL.
Bioorg Med Chem Lett (2005) 15 : 4342 -4344
PubMed 16039120 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 2 5.33 5.33

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL24720 ALPHA HYDROXY BENZYLPHOSPHONATE 1 5.33
CHEMBL1161801 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL24720 ALPHA HYDROXY BENZYLPHOSPHONATE Ki = 4700.0 nM 5.33
CHEMBL1161801 Ki = 1410000.0 nM -