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Target Snapshot

CHEMBL4739 Target Snapshot

Mandelate racemase · SINGLE PROTEIN · Pseudomonas putida

18Compounds
12Assays
0Approved Drugs
21.0Activities
Free Research Context

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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-14

Protein identity stays anchored to UniProt P11444. Use UniProt P11444 as the stable identity anchor, then attach disease evidence before program review.

Review focus
Protein anchor ready

Use UniProt P11444 as the stable identity anchor, then attach disease evidence before program review.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-14
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Mandelate racemase as ChEMBL target CHEMBL4739, mapped to UniProt P11444. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Mandelate racemase
SINGLE PROTEIN · Pseudomonas putida
As of 2026-09-14
ChEMBL target ID
CHEMBL4739
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-14
www.ebi.ac.uk
UniProt accession
P11444
Mandelate racemase
UniProt accession via ChEMBL component mapping As of 2026-09-14
www.uniprot.org
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-14
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

Choose the first block or source based on the question you are trying to answer.

Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Mandelate racemase is the right protein anchor across sources, using UniProt P11444 as the stable mapping.

Jump to Protein Context
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Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

Use this block first when you need the strongest disease program and evidence level in one place.

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

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UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelMandelate racemase
UniProt AccessionP11444
Component TypeProtein
Sequence Length359 aa

Mandelate racemase

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as Mandelate racemase, mapped to UniProt P11444. Sequence length is 359 aa.

Mapped IDP11444
Review nameMandelate racemase
OrganismPseudomonas putida
Assay Mix

Activity Type Distribution

KI21.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL1160299 5.96 Ki 1100.0 Preclinical
CHEMBL388471 5.57 Ki 2670.0 Preclinical
CHEMBL232642 5.55 Ki 2790.0 Preclinical
CHEMBL24720 5.33 Ki 4700.0 Preclinical
CHEMBL16300 4.92 Ki 12000.0 Preclinical
CHEMBL1160305 4.47 Ki 34000.0 Preclinical
Distribution

pChEMBL Value Distribution

2
5.0
3
5.5
0
6.0
0
6.5
0
7.0
0
7.5
0
8.0
0
8.5
0
9.0
0
9.5
pChEMBL
Assay Landscape

Assay Landscape

12
Total Assays
17
Tested Compounds
1
Assay Types
Binding — 12 assays, 17 compounds
BAO Format Assays Compounds Avg pChEMBL
single protein format 12 17 5.3

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine