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Compound Detail

CHEMBL232642

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O=CN(O)c1ccccc1

Basic Information

ChEMBL ID CHEMBL232642
Phase Preclinical
Structure Type MOL
InChI Key FWUDLKMCWUETIP-UHFFFAOYSA-N
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names

Molecular Properties

137.1
MW (Da)
1.04
ALogP
2
HBA
1
HBD
40.5
PSA (Ų)
0.38
QED
0
Ro5 Violations
2
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C7H7NO2
MW 137.14
Aromatic Rings 1
Heavy Atoms 10
NP-Likeness -0.31

Activity Summary

Ki 1 meas. best 5.55

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Mandelate racemase
CHEMBL4739
Ki 5.55 5.55 2790.0 1

Activity Data Samples

Top measurements by pChEMBL value

Target Type Rel. Value Units pChEMBL Assay PubMed
Mandelate racemase Ki = 2790.0 nM 5.55 Inhibition of mandelate racemase in Pseudomonas putida 17055725

Literature References

PubMed DOI Target Context # Activities
17055725 10.1016/j.bmcl.2006.09.079 Mandelate racemase 1
17055725 10.1016/j.bmcl.2006.09.079 No relevant target 1

Data from ChEMBL 36 via Core Engine