Assay Detail
Binding
CHEMBL885137
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Inhibitory concentration against P2Y purinoceptor 11 expressed in 1321N1 astrocytoma cells; n=7
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Synthesis and structure-activity relationships of suramin-derived P2Y11 receptor antagonists with nanomolar potency.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 7.15 | 7.35 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL413145 | — | — | 1 | 7.35 |
| CHEMBL413910 | — | — | 1 | 7.12 |
| CHEMBL413180 | — | — | 1 | 6.97 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL413145 | — | Ki | = | 44.67 | nM | 7.35 |
| CHEMBL413910 | — | Ki | = | 75.86 | nM | 7.12 |
| CHEMBL413180 | — | Ki | = | 107.15 | nM | 6.97 |