Assay Detail
Functional
CHEMBL886240
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Antiviral activity against EBV in GG68 cells after 72 hrs
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Human gammaherpesvirus 4 |
| Cell Type | GG68 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
2-Aryl-2-hydroxyethylamine substituted 4-oxo-4,7-dihydrothieno[2,3-b]pyridines as broad-spectrum inhibitors of human herpesvirus polymerases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.93 | 6.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL248161 | — | — | 1 | 6.70 |
| CHEMBL184 | ACYCLOVIR | 4.0 | 1 | 5.16 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL248161 | — | IC50 | = | 200.0 | nM | 6.70 |
| CHEMBL184 | ACYCLOVIR | IC50 | = | 6900.0 | nM | 5.16 |