Assay Detail
Functional
CHEMBL886378
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of IL8-induced migration of human neutrophils by chemotaxis assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | Neutrophil |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
C(4)-alkyl substituted furanyl cyclobutenediones as potent, orally bioavailable CXCR2 and CXCR1 receptor antagonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 7.43 | 7.43 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL246108 | — | — | 1 | 7.43 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL246108 | — | IC50 | = | 37.0 | nM | 7.43 |