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Assay Detail

CHEMBL886594

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against CD30 positive L540 Cy cells assessed as cell viability after 96 hrs
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Confidence 1 — Organism
Curated By Autocuration

Publication

Minor groove binder antibody conjugates employing a water soluble beta-glucuronide linker.
Jeffrey SC, Nguyen MT, Moser RF, Meyer DL, Miyamoto JB, Senter PD.
Bioorg Med Chem Lett (2007) 17 : 2278 -2280
PubMed 17293111 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 9.30 9.30

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL117142 1 9.30

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL117142 IC50 = 0.5 nM 9.30