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Assay Detail

CHEMBL886764

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Displacement of [125I]hCG from LH receptor
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Intermediate

Target

Lutropin-choriogonadotropic hormone receptor (CHEMBL1854)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Identification, synthesis, and biological evaluation of novel pyrazoles as low molecular weight luteinizing hormone receptor agonists.
Jorand-Lebrun C, Brondyk B, Lin J, Magar S, Murray R, Reddy A, Shroff H, Wands G, Weiser W, Xu Q, McKenna S, Brugger N.
Bioorg Med Chem Lett (2007) 17 : 2080 -2085
PubMed 17321742 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 9.51 9.51

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL246321 1 9.51

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL246321 Ki = 0.311 nM 9.51