Assay Detail
ADMET
CHEMBL887172
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Growth inhibition of mouse NIH3T3 cells by MTT assay
11
Total Activities
11
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Mus musculus |
| Cell Type | NIH3T3 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis and biological activity of 5-aza-ellipticine derivatives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 11 | 7.11 | 8.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL123 | ELLIPTECINE | — | 1 | 8.52 |
| CHEMBL393643 | — | — | 1 | 7.70 |
| CHEMBL247294 | — | — | 1 | 6.22 |
| CHEMBL391360 | — | — | 1 | 6.00 |
| CHEMBL247091 | — | — | 1 | - |
| CHEMBL247296 | — | — | 1 | - |
| CHEMBL239671 | — | — | 1 | - |
| CHEMBL392849 | — | — | 1 | - |
| CHEMBL247501 | — | — | 1 | - |
| CHEMBL247500 | — | — | 1 | - |
| CHEMBL391566 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL123 | ELLIPTECINE | IC50 | = | 3.0 | nM | 8.52 |
| CHEMBL393643 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL247294 | — | IC50 | = | 600.0 | nM | 6.22 |
| CHEMBL391360 | — | IC50 | = | 1000.0 | nM | 6.00 |
| CHEMBL247091 | — | IC50 | > | 1000.0 | nM | - |
| CHEMBL247296 | — | IC50 | - | — | - | |
| CHEMBL239671 | — | IC50 | - | — | - | |
| CHEMBL392849 | — | IC50 | - | — | - | |
| CHEMBL247501 | — | IC50 | - | — | - | |
| CHEMBL247500 | — | IC50 | - | — | - | |
| CHEMBL391566 | — | IC50 | - | — | - |