Assay Detail
Functional
CHEMBL887462
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Antiproliferative activity against human HL60 cells
10
Total Activities
10
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HL-60 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis and biological evaluation of 7-azaindole derivatives, synthetic cytokinin analogues.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 10 | 4.69 | 4.90 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL376177 | — | — | 1 | 4.90 |
| CHEMBL228792 | KINETIN | — | 1 | 4.66 |
| CHEMBL228917 | — | — | 1 | 4.63 |
| CHEMBL228844 | — | — | 1 | 4.63 |
| CHEMBL376178 | — | — | 1 | 4.62 |
| CHEMBL228862 | 6-BENZYLAMINOPURINE | — | 1 | - |
| CHEMBL376364 | — | — | 1 | - |
| CHEMBL228967 | — | — | 1 | - |
| CHEMBL376363 | — | — | 1 | - |
| CHEMBL228966 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL376177 | — | IC50 | = | 12600.0 | nM | 4.90 |
| CHEMBL228792 | KINETIN | IC50 | = | 21900.0 | nM | 4.66 |
| CHEMBL228917 | — | IC50 | = | 23600.0 | nM | 4.63 |
| CHEMBL228844 | — | IC50 | = | 23500.0 | nM | 4.63 |
| CHEMBL376178 | — | IC50 | = | 23700.0 | nM | 4.62 |
| CHEMBL228862 | 6-BENZYLAMINOPURINE | IC50 | > | 100000.0 | nM | - |
| CHEMBL376364 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL228967 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL376363 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL228966 | — | IC50 | > | 100000.0 | nM | - |