Assay Detail
Binding
CHEMBL888349
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human cathepsin L
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Intermediate |
Publication
Primary amides as selective inhibitors of cathepsin K.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.41 | 4.77 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL399359 | — | — | 1 | 4.77 |
| CHEMBL401176 | — | — | 1 | 4.25 |
| CHEMBL401175 | — | — | 1 | 4.20 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL399359 | — | IC50 | = | 17043.0 | nM | 4.77 |
| CHEMBL401176 | — | IC50 | = | 55728.0 | nM | 4.25 |
| CHEMBL401175 | — | IC50 | = | 63060.0 | nM | 4.20 |