Assay Detail
Binding
CHEMBL888500
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Displacement of [125I][Leu8-D-Trp22, Tyr25]-SRIF28 from human SST2 receptor
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
New sst4/5-selective somatostatin peptidomimetics based on a constrained tryptophan scaffold.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 6.84 | 7.08 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL227212 | — | — | 1 | 7.08 |
| CHEMBL374833 | — | — | 1 | 6.99 |
| CHEMBL227211 | — | — | 1 | 6.45 |
| CHEMBL388069 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL227212 | — | IC50 | = | 83.0 | nM | 7.08 |
| CHEMBL374833 | — | IC50 | = | 103.0 | nM | 6.99 |
| CHEMBL227211 | — | IC50 | = | 357.0 | nM | 6.45 |
| CHEMBL388069 | — | IC50 | > | 1000.0 | nM | - |