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Assay Detail

CHEMBL889041

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Inhibition of oxygen evolution rate in spinach chloroplasts
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Spinacia oleracea
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Synthesis and cytotoxic activity of trisubstituted-1,3,5-triazines.
Arya K, Dandia A.
Bioorg Med Chem Lett (2007) 17 : 3298 -3304
PubMed 17449247 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 8 4.91 5.72

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL278489 DCMU 1 5.72
CHEMBL243087 1 4.09
CHEMBL242650 1 -
CHEMBL244579 1 -
CHEMBL244377 1 -
CHEMBL244320 1 -
CHEMBL1455 ALTRETAMINE 4.0 1 -
CHEMBL395999 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL278489 DCMU IC50 = 1900.0 nM 5.72
CHEMBL243087 IC50 = 81000.0 nM 4.09
CHEMBL242650 IC50 = 1072000.0 nM -
CHEMBL244579 IC50 = 241000.0 nM -
CHEMBL244377 IC50 = 118000.0 nM -
CHEMBL244320 IC50 = 148000.0 nM -
CHEMBL1455 ALTRETAMINE IC50 = 486000.0 nM -
CHEMBL395999 IC50 = 244000.0 nM -