Assay Detail
Functional
CHEMBL889063
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antagonist activity at C3aR
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Target
C3a anaphylatoxin chemotactic receptor (CHEMBL4761) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Discovery of new C3aR ligands. Part 1: arginine derivatives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 4 | 5.73 | 6.80 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL230034 | — | — | 1 | 6.80 |
| CHEMBL229005 | — | — | 1 | 5.90 |
| CHEMBL228847 | — | — | 1 | 5.40 |
| CHEMBL390834 | — | — | 1 | 4.80 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL230034 | — | EC50 | = | 158.49 | nM | 6.80 |
| CHEMBL229005 | — | EC50 | = | 1258.93 | nM | 5.90 |
| CHEMBL228847 | — | EC50 | = | 3981.07 | nM | 5.40 |
| CHEMBL390834 | — | EC50 | = | 15848.93 | nM | 4.80 |