Assay Detail
Functional
CHEMBL889064
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Agonist activity at C3a receptor expressed on HMC1 cells
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HMC1 |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Target
C3a anaphylatoxin chemotactic receptor (CHEMBL4761) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Discovery of new C3aR ligands. Part 1: arginine derivatives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 6.97 | 7.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL387755 | — | — | 1 | 7.70 |
| CHEMBL229006 | — | — | 1 | 6.90 |
| CHEMBL231405 | — | — | 1 | 6.30 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL387755 | — | EC50 | = | 19.95 | nM | 7.70 |
| CHEMBL229006 | — | EC50 | = | 125.89 | nM | 6.90 |
| CHEMBL231405 | — | EC50 | = | 501.19 | nM | 6.30 |