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Assay Detail

CHEMBL889722

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of human FGFR1 kinase expressed in insect cell by HTRF detection method
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Expert

Target

Fibroblast growth factor receptor 1 (CHEMBL3650)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Novel inhibitor for fibroblast growth factor receptor tyrosine kinase.
Kammasud N, Boonyarat C, Tsunoda S, Sakurai H, Saiki I, Grierson DS, Vajragupta O.
Bioorg Med Chem Lett (2007) 17 : 4812 -4818
PubMed 17618113 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 6.16 6.40

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL231526 1 6.40
CHEMBL358728 1 5.92

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL231526 IC50 = 400.0 nM 6.40
CHEMBL358728 IC50 = 1200.0 nM 5.92