Assay Detail
Functional
CHEMBL890043
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of MDC-induced chemotaxis in L1.2 cells expressing CCR4
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | L1.2 |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Core exploration in optimization of chemokine receptor CCR4 antagonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.73 | 8.15 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL233046 | — | — | 1 | 8.15 |
| CHEMBL233047 | — | — | 1 | 5.30 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL233046 | — | IC50 | = | 7.0 | nM | 8.15 |
| CHEMBL233047 | — | IC50 | = | 5000.0 | nM | 5.30 |