Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL890102

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of HCV 1a NS3 protease
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Hepatitis C virus subtype 1a
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

NS3 (CHEMBL1293269)
Type SINGLE PROTEIN
Organism Hepatitis C virus

Publication

Phenylglycine as a novel P2 scaffold in hepatitis C virus NS3 protease inhibitors.
Ortqvist P, Peterson SD, Kerblom E, Gossas T, Sabnis YA, Fransson R, Lindeberg G, Helena Danielson U, Karlén A, Sandström A.
Bioorg Med Chem (2007) 15 : 1448 -1474
PubMed 17113777 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 9.52 9.52

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL297884 CILUPREVIR 2.0 1 9.52

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL297884 CILUPREVIR Ki = 0.3 nM 9.52