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Assay Detail

CHEMBL890920

Review assay metadata, readout intent, target linkage, and publication context from the same page.

ADMET
Cytotoxicity against J774.1 cells after 48 hrs
11
Total Activities
11
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type ADMET
Organism Mus musculus
Cell Type J774.1
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

ADMET (CHEMBL612558)
Type ADMET

Publication

Antitrypanosomal activity of quaternary naphthalimide derivatives.
Muth M, Hoerr V, Glaser M, Ponte-Sucre A, Moll H, Stich A, Holzgrabe U.
Bioorg Med Chem Lett (2007) 17 : 1590 -1593
PubMed 17239596 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 11 5.49 5.49

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL388891 1 5.49
CHEMBL233476 1 -
CHEMBL8532 1 -
CHEMBL269592 1 -
CHEMBL397958 1 -
CHEMBL388470 1 -
CHEMBL390702 1 -
CHEMBL233049 1 -
CHEMBL406691 1 -
CHEMBL8449 1 -
CHEMBL389344 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL388891 IC50 = 3240.0 nM 5.49
CHEMBL233476 IC50 > 100000.0 nM -
CHEMBL8532 IC50 > 100000.0 nM -
CHEMBL269592 IC50 > 100000.0 nM -
CHEMBL397958 IC50 > 100000.0 nM -
CHEMBL388470 IC50 > 100000.0 nM -
CHEMBL390702 IC50 > 100000.0 nM -
CHEMBL233049 IC50 > 100000.0 nM -
CHEMBL406691 IC50 > 100000.0 nM -
CHEMBL8449 IC50 > 100000.0 nM -
CHEMBL389344 IC50 > 100000.0 nM -