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Assay Detail

CHEMBL891359

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Inhibition of Chlorella vulgaris Beij assessed as reduction of chlorophyll content
18
Total Activities
18
Compounds Tested
2
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Chlorella vulgaris
Confidence 1 — Organism
Curated By Autocuration

Target

Chlorella vulgaris (CHEMBL613342)
Type ORGANISM
Organism Chlorella vulgaris

Publication

Investigating biological activity spectrum for novel quinoline analogues.
Musiol R, Jampilek J, Kralova K, Richardson DR, Kalinowski D, Podeszwa B, Finster J, Niedbala H, Palka A, Polanski J.
Bioorg Med Chem (2007) 15 : 1280 -1288
PubMed 17142046 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 17 4.57 5.14
Activity 1 - -

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL278489 DCMU 1 5.14
CHEMBL242547 1 4.96
CHEMBL242763 1 4.77
CHEMBL202312 1 4.48
CHEMBL242107 1 4.02
CHEMBL427867 1 4.02
CHEMBL395093 1 -
CHEMBL395092 1 -
CHEMBL242108 1 -
CHEMBL397907 1 -
CHEMBL241898 1 -
CHEMBL242546 1 -
CHEMBL241908 1 -
CHEMBL428035 1 -
CHEMBL241906 1 -
CHEMBL202369 1 -
CHEMBL242110 1 -
CHEMBL242109 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL278489 DCMU IC50 = 7300.0 nM 5.14
CHEMBL242547 IC50 = 11000.0 nM 4.96
CHEMBL242763 IC50 = 17000.0 nM 4.77
CHEMBL202312 IC50 = 33000.0 nM 4.48
CHEMBL242107 IC50 = 95000.0 nM 4.02
CHEMBL427867 IC50 = 96000.0 nM 4.02
CHEMBL395093 IC50 = 168000.0 nM -
CHEMBL395092 Activity - -
CHEMBL242108 IC50 = 114000.0 nM -
CHEMBL397907 IC50 = 115000.0 nM -
CHEMBL241898 IC50 - -
CHEMBL242546 IC50 - -
CHEMBL241908 IC50 - -
CHEMBL428035 IC50 - -
CHEMBL241906 IC50 - -
CHEMBL202369 IC50 - -
CHEMBL242110 IC50 - -
CHEMBL242109 IC50 - -