Assay Detail
Functional
CHEMBL892191
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Antitumor activity against HL60 cells after 6 hrs by MTT assay
3
Total Activities
3
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HL-60 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis of the new pseudo-symmetrical tamoxifen derivatives and their anti-tumor activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.41 | 5.52 |
| Activity | 1 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL392916 | — | — | 1 | 5.52 |
| CHEMBL393196 | — | — | 1 | 5.30 |
| CHEMBL235994 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL392916 | — | IC50 | = | 3000.0 | nM | 5.52 |
| CHEMBL393196 | — | IC50 | = | 5000.0 | nM | 5.30 |
| CHEMBL235994 | — | Activity | - | — | - |