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Assay Detail

CHEMBL892193

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antitumor activity against HL60 cells after 3 hrs by MTT assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type HL-60
Confidence 1 — Organism
Curated By Autocuration

Target

HL-60 (CHEMBL383)
Type CELL-LINE
Organism Homo sapiens

Publication

Synthesis of the new pseudo-symmetrical tamoxifen derivatives and their anti-tumor activity.
Shiina I, Sano Y, Nakata K, Kikuchi T, Sasaki A, Ikekita M, Hasome Y.
Bioorg Med Chem Lett (2007) 17 : 2421 -2424
PubMed 17346960 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.40 5.40

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL392916 1 5.40

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL392916 IC50 = 4000.0 nM 5.40