Assay Detail
Functional
CHEMBL893265
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against HIV1 3B in MT4 cells at 200 uM
5
Total Activities
3
Compounds Tested
4
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Human immunodeficiency virus 1 |
| Cell Type | MT4 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Target
Human immunodeficiency virus 1 (CHEMBL378) ↗| Type | ORGANISM |
| Organism | Human immunodeficiency virus 1 |
Publication
Caffeoylglycolic and caffeoylamino acid derivatives, halfmers of L-chicoric acid, as new HIV-1 integrase inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Activity | 2 | - | - |
| CC50 | 1 | - | - |
| EC50 | 1 | 5.12 | 5.12 |
| TI | 1 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL397730 | — | — | 3 | 5.12 |
| CHEMBL244868 | — | — | 1 | - |
| CHEMBL442795 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL397730 | — | EC50 | = | 7500.0 | nM | 5.12 |
| CHEMBL397730 | — | CC50 | = | 42200.0 | nM | - |
| CHEMBL397730 | — | TI | = | 5.6 | — | - |
| CHEMBL244868 | — | Activity | - | — | - | |
| CHEMBL442795 | — | Activity | - | — | - |