Assay Detail
Functional
CHEMBL893388
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Growth inhibition of human A431 cells by MTT assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | A-431 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Radioiodination of new EGFR inhibitors as potential SPECT agents for molecular imaging of breast cancer.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.27 | 5.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL279329 | — | — | 1 | 5.70 |
| CHEMBL394574 | — | — | 1 | 5.52 |
| CHEMBL242541 | — | — | 1 | 4.60 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL279329 | — | IC50 | = | 2000.0 | nM | 5.70 |
| CHEMBL394574 | — | IC50 | = | 3000.0 | nM | 5.52 |
| CHEMBL242541 | — | IC50 | = | 25000.0 | nM | 4.60 |