Assay Detail
Functional
CHEMBL894014
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Cytotoxicity against mouse LLC cells
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | Lewis lung carcinoma |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Spectroscopic studies of DNA binding modes of cation-substituted anthrapyrazoles derived from emodin.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.10 | 5.35 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL243249 | — | — | 1 | 5.35 |
| CHEMBL244950 | — | — | 1 | 5.05 |
| CHEMBL244745 | — | — | 1 | 4.89 |
| CHEMBL289277 | EMODIN | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL243249 | — | IC50 | = | 4500.0 | nM | 5.35 |
| CHEMBL244950 | — | IC50 | = | 8900.0 | nM | 5.05 |
| CHEMBL244745 | — | IC50 | = | 12800.0 | nM | 4.89 |
| CHEMBL289277 | EMODIN | IC50 | > | 100000.0 | nM | - |