Assay Detail
Functional
CHEMBL894024
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Growth inhibition of MS1 cells by XTT assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Cell Type | MS1 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Highly potent inhibitors of methionine aminopeptidase-2 based on a 1,2,4-triazole pharmacophore.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.46 | 7.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL444369 | — | — | 1 | 7.00 |
| CHEMBL230005 | — | — | 1 | 6.85 |
| CHEMBL243303 | — | — | 1 | 5.52 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL444369 | — | IC50 | = | 100.0 | nM | 7.00 |
| CHEMBL230005 | — | IC50 | = | 140.0 | nM | 6.85 |
| CHEMBL243303 | — | IC50 | = | 3000.0 | nM | 5.52 |